Rapid-antigen detection tests for group a streptococcal pharyngitis: revisiting false-positive results using polymerase chain reaction testing.
J Pediatr
; 162(6): 1282-4, 1284.e1, 2013 Jun.
Article
en En
| MEDLINE
| ID: mdl-23465407
ABSTRACT
We investigated mechanisms of the false-positive test results on rapid-antigen detection test (RADT) for group A Streptococcal (GAS) pharyngitis. Most RADT false-positives (76%) were associated with polymerase chain reaction-positive GAS results, suggesting that RADT specificity could be considered close to 100%. Finding that 61% of GAS culture-negative but RADT-positive cases were positive on both GAS polymerase chain reaction and Staphylococcus aureus testing, we posit bacterial inhibition as causative.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Faringe
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Staphylococcus aureus
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Infecciones Estreptocócicas
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Streptococcus pyogenes
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Faringitis
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Antígenos Bacterianos
Tipo de estudio:
Diagnostic_studies
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Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
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Child
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Child, preschool
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Humans
Idioma:
En
Revista:
J Pediatr
Año:
2013
Tipo del documento:
Article
País de afiliación:
Francia