Enantioselective fluoroamination: 1,4-addition to conjugated dienes using anionic phase-transfer catalysis.
Angew Chem Int Ed Engl
; 52(30): 7724-7, 2013 Jul 22.
Article
en En
| MEDLINE
| ID: mdl-23766145
ABSTRACT
Chiral-anion phase-transfer catalysis (PTC) has been applied towards the enantioselective fluorocyclization reactions of 1,3-dienes. The method affords unprecedented fluorinated benz[f]isoquinoline and octahydroisoquinoline products in high yields and up to 96 % ee. New fluorinated amine reagents outperformed Selectfluor in the desired transformation.
Texto completo:
1
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos