Wall shear stress distribution at the carotid bifurcation: influence of eversion carotid endarterectomy.
Eur Radiol
; 23(12): 3361-9, 2013 Dec.
Article
en En
| MEDLINE
| ID: mdl-23812310
ABSTRACT
OBJECTIVES:
To test the feasibility of four-dimensional (4D) flow MRI to quantify the systolic wall shear stress (WSSsystole) and oscillatory shear index (OSI) in high-grade internal carotid artery (ICA) stenosis before and after endarterectomy (CEA).METHODS:
Twenty patients with ≥60 % ICA stenosis were prospectively and consequently included. Four-dimensional flow MRI was used to measure individual time-resolved 3D blood flow velocities. Segmental WSSsystole and OSI were derived at eight wall segments in analysis planes positioned along the ICA, common (CCA) and external carotid artery (ECA).RESULTS:
Regional WSSsystole of all patients decreased after CEA (P < 0.05). Changes were most prominent at the ICA bulb but remained unchanged in the CCA and ECA. OSI was significantly lower after CEA in the lateral vessel walls (P < 0.05). For analysis planes at the stenosis in- and outlet, a reduction of mean WSSsystole by 32 % and 52 % (P < 0.001) and OSI distal to the stenosis (40 %, P = 0.01) was found after CEA.CONCLUSIONS:
Our findings show the potential of in vivo 4D flow MRI to quantify haemodynamic changes in wall shear stress even in patients with complex flow conditions.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
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Arteria Carótida Interna
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Endarterectomía Carotidea
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Estenosis Carotídea
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Hemodinámica
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
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Observational_studies
Límite:
Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Eur Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2013
Tipo del documento:
Article