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HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.
Caza, Tiffany N; Fernandez, David R; Talaber, Gergely; Oaks, Zachary; Haas, Mark; Madaio, Michael P; Lai, Zhi-Wei; Miklossy, Gabriella; Singh, Ram R; Chudakov, Dmitriy M; Malorni, Walter; Middleton, Frank; Banki, Katalin; Perl, Andras.
Afiliación
  • Caza TN; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Fernandez DR; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Talaber G; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Oaks Z; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Haas M; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
  • Madaio MP; Department of Medicine, Medical College of Georgia, Augusta, Georgia, USA.
  • Lai ZW; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Miklossy G; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Singh RR; Department of Medicine, UCLA, Los Angeles, California, USA.
  • Chudakov DM; Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia.
  • Malorni W; Department of Experimental Medicine, University of Rome, Rome, Italy.
  • Middleton F; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Banki K; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
  • Perl A; Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA.
Ann Rheum Dis ; 73(10): 1888-97, 2014 Oct.
Article en En | MEDLINE | ID: mdl-23897774
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al GTP rab4 / Proteínas Mitocondriales / GTP Fosfohidrolasas / Lupus Eritematoso Sistémico / Proteínas Asociadas a Microtúbulos / Mitocondrias Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Ann Rheum Dis Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al GTP rab4 / Proteínas Mitocondriales / GTP Fosfohidrolasas / Lupus Eritematoso Sistémico / Proteínas Asociadas a Microtúbulos / Mitocondrias Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Ann Rheum Dis Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos