Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma.

Zhang, Xiang H-F; Jin, Xin; Malladi, Srinivas; Zou, Yilong; Wen, Yong H; Brogi, Edi; Smid, Marcel; Foekens, John A; Massagué, Joan

Zhang, Xiang H-F; Jin, Xin; Malladi, Srinivas; Zou, Yilong; Wen, Yong H; Brogi, Edi; Smid, Marcel; Foekens, John A; Massagué, Joan.

Afiliación

Zhang XH; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Jin X; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Malladi S; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Zou Y; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Wen YH; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Brogi E; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Smid M; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CE Rotterdam, the Netherlands.
Foekens JA; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CE Rotterdam, the Netherlands.
Massagué J; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD 21205, USA. Electronic address: j-massague@ski.mskcc.org.

Cell ; 154(5): 1060-1073, 2013 Aug 29.

Article en En | MEDLINE | ID: mdl-23993096

Asunto(s)

Neoplasias Óseas/secundario; Neoplasias de la Mama/patología; Metástasis de la Neoplasia; Transducción de Señal; Animales; Médula Ósea/metabolismo; Neoplasias Óseas/metabolismo; Neoplasias de la Mama/genética; Neoplasias de la Mama/metabolismo; Quimiocina CXCL12/metabolismo; Fibroblastos/metabolismo; Humanos; Factor I del Crecimiento Similar a la Insulina/metabolismo; Células Madre Mesenquimatosas/metabolismo; Células Madre Mesenquimatosas/patología; Ratones; Trasplante de Neoplasias; Transcripción Genética; Trasplante Heterólogo; Familia-src Quinasas/genética; Familia-src Quinasas/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Óseas / Neoplasias de la Mama / Transducción de Señal / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Año: 2013 Tipo del documento: Article País de afiliación: Estados Unidos

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