Effect of resveratrol on mitochondrial function: implications in parkin-associated familiar Parkinson's disease.

Ferretta, Anna; Gaballo, Antonio; Tanzarella, Paola; Piccoli, Claudia; Capitanio, Nazzareno; Nico, Beatrice; Annese, Tiziana; Di Paola, Marco; Dell'aquila, Claudia; De Mari, Michele; Ferranini, Ermanno; Bonifati, Vincenzo; Pacelli, Consiglia; Cocco, Tiziana

Ferretta, Anna; Gaballo, Antonio; Tanzarella, Paola; Piccoli, Claudia; Capitanio, Nazzareno; Nico, Beatrice; Annese, Tiziana; Di Paola, Marco; Dell'aquila, Claudia; De Mari, Michele; Ferranini, Ermanno; Bonifati, Vincenzo; Pacelli, Consiglia; Cocco, Tiziana.

Afiliación

Ferretta A; Department of Basic Medical Sciences, Neurosciences and Organs of Senses, University of Bari 'A. Moro', Bari, Italy.
Gaballo A; Institute of Nanoscience-NNL, Consiglio Nazionale delle Ricerche (CNR), Lecce, Italy.
Tanzarella P; Department of Basic Medical Sciences, Neurosciences and Organs of Senses, University of Bari 'A. Moro', Bari, Italy.
Piccoli C; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Capitanio N; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Nico B; Department of Basic Medical Sciences, Neurosciences and Organs of Senses, University of Bari 'A. Moro', Bari, Italy.
Annese T; Department of Basic Medical Sciences, Neurosciences and Organs of Senses, University of Bari 'A. Moro', Bari, Italy.
Di Paola M; Institute of Biomembranes and Bioenergetics, Consiglio Nazionale delle Ricerche, (CNR), Bari, Italy.
Dell'aquila C; Department of Neurology, 'Bonomo' Hospital, Andria (BA), Italy.
De Mari M; Department of Neurology, 'Bonomo' Hospital, Andria (BA), Italy.
Ferranini E; Department of Neurology, 'Madonnina' Hospital, Bari, Italy.
Bonifati V; Department of Clinical Genetics, Erasmus MC, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.
Pacelli C; Department of Basic Medical Sciences, Neurosciences and Organs of Senses, University of Bari 'A. Moro', Bari, Italy. Electronic address: consiglia.pacelli@umontreal.ca.
Cocco T; Department of Basic Medical Sciences, Neurosciences and Organs of Senses, University of Bari 'A. Moro', Bari, Italy. Electronic address: tizianamaria.cocco@uniba.it.

Biochim Biophys Acta ; 1842(7): 902-15, 2014 Jul.

Article en En | MEDLINE | ID: mdl-24582596

Asunto(s)

Mitocondrias/efectos de los fármacos; Enfermedad de Parkinson/tratamiento farmacológico; Enfermedad de Parkinson/fisiopatología; Estilbenos/farmacología; Ubiquitina-Proteína Ligasas/genética; Ubiquitina-Proteína Ligasas/metabolismo; Proteínas Quinasas Activadas por AMP/genética; Proteínas Quinasas Activadas por AMP/metabolismo; Adenosina Trifosfato/genética; Adenosina Trifosfato/metabolismo; Células Cultivadas; Femenino; Fibroblastos/efectos de los fármacos; Fibroblastos/metabolismo; Predisposición Genética a la Enfermedad; Humanos; Persona de Mediana Edad; Mitocondrias/genética; Mitocondrias/metabolismo; NAD/genética; NAD/metabolismo; Estrés Oxidativo/efectos de los fármacos; Estrés Oxidativo/genética; Consumo de Oxígeno/efectos de los fármacos; Consumo de Oxígeno/genética; Enfermedad de Parkinson/genética; Enfermedad de Parkinson/metabolismo; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma; Resveratrol; Sirtuina 1/genética; Sirtuina 1/metabolismo; Factores de Transcripción/genética; Factores de Transcripción/metabolismo

Palabras clave

Mitochondria; PGC-1α; Parkin; Parkinson's disease; Resveratrol; Sirtuin 1

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Estilbenos / Ubiquitina-Proteína Ligasas / Mitocondrias Tipo de estudio: Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Biochim Biophys Acta Año: 2014 Tipo del documento: Article País de afiliación: Italia

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