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Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers.
Hattne, Johan; Echols, Nathaniel; Tran, Rosalie; Kern, Jan; Gildea, Richard J; Brewster, Aaron S; Alonso-Mori, Roberto; Glöckner, Carina; Hellmich, Julia; Laksmono, Hartawan; Sierra, Raymond G; Lassalle-Kaiser, Benedikt; Lampe, Alyssa; Han, Guangye; Gul, Sheraz; DiFiore, Dörte; Milathianaki, Despina; Fry, Alan R; Miahnahri, Alan; White, William E; Schafer, Donald W; Seibert, M Marvin; Koglin, Jason E; Sokaras, Dimosthenis; Weng, Tsu-Chien; Sellberg, Jonas; Latimer, Matthew J; Glatzel, Pieter; Zwart, Petrus H; Grosse-Kunstleve, Ralf W; Bogan, Michael J; Messerschmidt, Marc; Williams, Garth J; Boutet, Sébastien; Messinger, Johannes; Zouni, Athina; Yano, Junko; Bergmann, Uwe; Yachandra, Vittal K; Adams, Paul D; Sauter, Nicholas K.
Afiliación
  • Hattne J; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Echols N; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Tran R; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Kern J; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Gildea RJ; 1] Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA. [2].
  • Brewster AS; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Alonso-Mori R; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Glöckner C; Max-Volmer-Laboratorium für Biophysikalische Chemie, Technische Universität, Berlin, Germany.
  • Hellmich J; Max-Volmer-Laboratorium für Biophysikalische Chemie, Technische Universität, Berlin, Germany.
  • Laksmono H; Stanford PULSE Institute, SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Sierra RG; Stanford PULSE Institute, SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Lassalle-Kaiser B; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Lampe A; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Han G; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Gul S; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • DiFiore D; Max-Volmer-Laboratorium für Biophysikalische Chemie, Technische Universität, Berlin, Germany.
  • Milathianaki D; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Fry AR; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Miahnahri A; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • White WE; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Schafer DW; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Seibert MM; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Koglin JE; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Sokaras D; Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Weng TC; Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Sellberg J; 1] Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, USA. [2] Department of Physics, AlbaNova, Stockholm University, Stockholm, Sweden.
  • Latimer MJ; Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Glatzel P; European Synchrotron Radiation Facility, Grenoble, France.
  • Zwart PH; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Grosse-Kunstleve RW; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Bogan MJ; 1] Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA. [2] Stanford PULSE Institute, SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Messerschmidt M; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Williams GJ; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Boutet S; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Messinger J; Institutionen för Kemi, Kemiskt Biologiskt Centrum, Umeå Universitet, Umeå, Sweden.
  • Zouni A; 1] Max-Volmer-Laboratorium für Biophysikalische Chemie, Technische Universität, Berlin, Germany. [2] Institut für Biologie, Humboldt Universität zu Berlin, Berlin, Germany.
  • Yano J; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Bergmann U; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California, USA.
  • Yachandra VK; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Adams PD; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Sauter NK; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Nat Methods ; 11(5): 545-8, 2014 May.
Article en En | MEDLINE | ID: mdl-24633409
ABSTRACT
X-ray free-electron laser (XFEL) sources enable the use of crystallography to solve three-dimensional macromolecular structures under native conditions and without radiation damage. Results to date, however, have been limited by the challenge of deriving accurate Bragg intensities from a heterogeneous population of microcrystals, while at the same time modeling the X-ray spectrum and detector geometry. Here we present a computational approach designed to extract meaningful high-resolution signals from fewer diffraction measurements.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sustancias Macromoleculares / Rayos Láser Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Methods Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sustancias Macromoleculares / Rayos Láser Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Methods Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos