Synthesis and antiviral activity of a novel glycosyl sulfoxide against classical swine fever virus.

Krol, Ewelina; Pastuch-Gawolek, Gabriela; Nidzworski, Dawid; Rychlowski, Michal; Szeja, Wieslaw; Grynkiewicz, Grzegorz; Szewczyk, Boguslaw

Krol, Ewelina; Pastuch-Gawolek, Gabriela; Nidzworski, Dawid; Rychlowski, Michal; Szeja, Wieslaw; Grynkiewicz, Grzegorz; Szewczyk, Boguslaw.

Afiliación

Krol E; Department of Recombinant Vaccines, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Kladki 24, 80-822 Gdansk, Poland. Electronic address: ewelina@biotech.ug.gda.pl.
Pastuch-Gawolek G; Department of Organic Chemistry, Bioorganic Chemistry and Biotechnology, Faculty of Chemistry, Silesian University of Technology, Krzywoustego 4, 44-101 Gliwice, Poland.
Nidzworski D; Department of Recombinant Vaccines, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Kladki 24, 80-822 Gdansk, Poland.
Rychlowski M; Department of Virus Molecular Biology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Kladki 24, 80-822 Gdansk, Poland.
Szeja W; Department of Organic Chemistry, Bioorganic Chemistry and Biotechnology, Faculty of Chemistry, Silesian University of Technology, Krzywoustego 4, 44-101 Gliwice, Poland.
Grynkiewicz G; Pharmaceutical Research Institute, Rydygiera 8, 01-793 Warsaw, Poland.
Szewczyk B; Department of Recombinant Vaccines, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Kladki 24, 80-822 Gdansk, Poland.

Bioorg Med Chem ; 22(9): 2662-70, 2014 May 01.

Article en En | MEDLINE | ID: mdl-24721828

Asunto(s)

Antivirales/síntesis química; Safrol/análogos & derivados; Animales; Antivirales/química; Antivirales/toxicidad; Línea Celular; Supervivencia Celular/efectos de los fármacos; Virus de la Fiebre Porcina Clásica/efectos de los fármacos; Glicoproteínas/genética; Glicoproteínas/metabolismo; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Safrol/síntesis química; Safrol/química; Safrol/toxicidad; Porcinos; Proteínas del Envoltorio Viral/genética; Proteínas del Envoltorio Viral/metabolismo

Palabras clave

Classical swine fever virus; Glycoproteins; Sulfoxides

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Safrol Límite: Animals Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article

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