Absence of in vivo genotoxicity of 3-monochloropropane-1,2-diol and associated fatty acid esters in a 4-week comprehensive toxicity study using F344 gpt delta rats.

Onami, Saeko; Cho, Young-Man; Toyoda, Takeshi; Horibata, Katsuyoshi; Ishii, Yuji; Umemura, Takashi; Honma, Masamitsu; Nohmi, Takehiko; Nishikawa, Akiyoshi; Ogawa, Kumiko

Onami, Saeko; Cho, Young-Man; Toyoda, Takeshi; Horibata, Katsuyoshi; Ishii, Yuji; Umemura, Takashi; Honma, Masamitsu; Nohmi, Takehiko; Nishikawa, Akiyoshi; Ogawa, Kumiko.

Afiliación

Onami S; Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan, Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan, and.
Cho YM; Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
Toyoda T; Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
Horibata K; Division of Genetics and Mutagenesis and.
Ishii Y; Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
Umemura T; Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan, Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan, and.
Honma M; Division of Genetics and Mutagenesis and.
Nohmi T; Division of Genetics and Mutagenesis and.
Nishikawa A; Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan, and Biological Safety Research Center, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
Ogawa K; Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan, ogawa93@nihs.go.jp.

Mutagenesis ; 29(4): 295-302, 2014 Jul.

Article en En | MEDLINE | ID: mdl-24831098

Asunto(s)

Ésteres/metabolismo; Ácidos Grasos/metabolismo; Mutágenos/toxicidad; Pentosiltransferasa/genética; alfa-Clorhidrina/toxicidad; Animales; Peso Corporal/efectos de los fármacos; Pruebas de Enzimas; Femenino; Humanos; Riñón/efectos de los fármacos; Riñón/patología; Masculino; Proteínas de la Membrana/genética; Pruebas de Micronúcleos; Pruebas de Mutagenicidad; Mutación/genética; Tamaño de los Órganos/efectos de los fármacos; Ratas Endogámicas F344; Ratas Transgénicas

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pentosiltransferasa / Ésteres / Alfa-Clorhidrina / Ácidos Grasos / Mutágenos Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Mutagenesis Asunto de la revista: GENETICA MEDICA / SAUDE AMBIENTAL Año: 2014 Tipo del documento: Article

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