High-dose tamoxifen plus ifosfamide and anthracycline in a patient with angiosarcoma of the breast.
West Indian Med J
; 62(7): 651-3, 2013 Sep.
Article
en En
| MEDLINE
| ID: mdl-24831906
ABSTRACT
Although breast cancer is, unfortunately, not uncommon in women, a mere 0.04% of malignant breast tumours are primary angiosarcomas. Chemotherapy is advocated for treatment of breast angiosarcomas; however, no guidelines exist regarding optimal chemotherapeutics or protocols. Presently, the prognosis for breast angiosarcomas is poor. This case report describes a 24-year old woman diagnosed with primary breast angiosarcoma. She initially refused to receive treatment, but later returned to the hospital four years later with a haemopneumothorax. She was treated with rescue chemotherapy using a combination of high-dose tamoxifen plus ifosfamide and epirubicin (an anthracycline). She achieved a partial response, but died 16 months after therapy was initiated. More research is needed to devise novel chemotherapeutics and protocols to improve outcomes in women diagnosed with primary angiosarcomas of the breast.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias de la Mama
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Hemangiosarcoma
Tipo de estudio:
Guideline
/
Prognostic_studies
Límite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
West Indian Med J
Año:
2013
Tipo del documento:
Article
País de afiliación:
Taiwán