In vivo imaging in an ABSL-3 regional biocontainment laboratory.
Pathog Dis
; 71(2): 207-12, 2014 Jul.
Article
en En
| MEDLINE
| ID: mdl-24838691
ABSTRACT
The Regional Biocontainment Laboratory (RBL) at the University of Pittsburgh is a state-of-the-art ABSL-3 facility that supports research on highly pathogenic viruses and bacteria. Recent advances in radiologic imaging provide several noninvasive, in vivo imaging modalities that can be used to longitudinally monitor animals following experimental infection or vaccination. The University of Pittsburgh RBL provides digital radiography, bioluminescence imaging, and PET/CT. Operating these platforms in an ABSL-3 poses unique challenges. This review will discuss the development and refinement of these imaging platforms in high containment, emphasizing specific challenges and how they were overcome.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Infecciones Bacterianas
/
Virosis
/
Contención de Riesgos Biológicos
/
Imagen Óptica
Tipo de estudio:
Prognostic_studies
Límite:
Animals
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Pathog Dis
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos