Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families.

Rees, Matthew G; Raimondo, Anne; Wang, Jian; Ban, Matthew R; Davis, Mindy I; Barrett, Amy; Ranft, Jessica; Jagdhuhn, David; Waterstradt, Rica; Baltrusch, Simone; Simeonov, Anton; Collins, Francis S; Hegele, Robert A; Gloyn, Anna L

Rees, Matthew G; Raimondo, Anne; Wang, Jian; Ban, Matthew R; Davis, Mindy I; Barrett, Amy; Ranft, Jessica; Jagdhuhn, David; Waterstradt, Rica; Baltrusch, Simone; Simeonov, Anton; Collins, Francis S; Hegele, Robert A; Gloyn, Anna L.

Afiliación

Rees MG; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LE, UK, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 2
Raimondo A; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LE, UK.
Wang J; Departments of Medicine and Biochemistry, Schulich School of Medicine and Dentistry, Robarts Research Institute, University of Western Ontario, London, ON N6A 3K6, Canada.
Ban MR; Departments of Medicine and Biochemistry, Schulich School of Medicine and Dentistry, Robarts Research Institute, University of Western Ontario, London, ON N6A 3K6, Canada.
Davis MI; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.
Barrett A; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LE, UK.
Ranft J; Institute for Medical Biochemistry & Molecular Biology, University of Rostock, Rostock 18057, Germany and.
Jagdhuhn D; Institute for Medical Biochemistry & Molecular Biology, University of Rostock, Rostock 18057, Germany and.
Waterstradt R; Institute for Medical Biochemistry & Molecular Biology, University of Rostock, Rostock 18057, Germany and.
Baltrusch S; Institute for Medical Biochemistry & Molecular Biology, University of Rostock, Rostock 18057, Germany and.
Simeonov A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.
Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Hegele RA; Departments of Medicine and Biochemistry, Schulich School of Medicine and Dentistry, Robarts Research Institute, University of Western Ontario, London, ON N6A 3K6, Canada.
Gloyn AL; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LE, UK, NIHR Oxford Biomedical Research Centre, ORH Trust, OCDEM, Churchill Hospital, Oxford OX3 7LE, UK anna.gloyn@drl.ox.ac.uk.

Hum Mol Genet ; 23(20): 5570-8, 2014 Oct 15.

Article en En | MEDLINE | ID: mdl-24879641

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/genética; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Hiperlipoproteinemia Tipo IV/genética; Polimorfismo de Nucleótido Simple; Triglicéridos/sangre; Proteínas Adaptadoras Transductoras de Señales/química; Algoritmos; Animales; Células COS; Estudios de Casos y Controles; Chlorocebus aethiops; Variación Genética; Células HeLa; Humanos; Hiperlipoproteinemia Tipo IV/sangre; Ratones; Modelos Moleculares; Estructura Terciaria de Proteína; Análisis de Secuencia de ADN

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triglicéridos / Polimorfismo de Nucleótido Simple / Proteínas Adaptadoras Transductoras de Señales / Hiperlipoproteinemia Tipo IV Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2014 Tipo del documento: Article

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