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Significant improvement in mild acne following a twice daily application for 6 weeks of an acidic cleansing product (pH 4).
Abels, Christoph; Reich, Hubert; Knie, Ulrich; Werdier, Dieter; Lemmnitz, Gunter.
Afiliación
  • Abels C; Dr. August Wolff GmbH & Co. KG Arzneimittel, Bielefeld, Germany.
J Cosmet Dermatol ; 13(2): 103-8, 2014 Jun.
Article en En | MEDLINE | ID: mdl-24910273
BACKGROUND: Cleansing products for acne should remove excessive sebum, reduce acne-related bacteria and improve inflammation. AIMS: The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris. METHODS: Sixty patients were recruited for this open uncontrolled clinical trial. The tested product was exclusively applied twice a day for 6 weeks. The efficacy was judged by a dermatologist according to the Leeds score after 3 and 6 weeks. In addition, efficacy and tolerability were judged subjectively by physician and patients. RESULTS: Mild acne improved significantly after 6 weeks (baseline: 0.699 vs. day 42: 0.602; P < 0.001). Efficacy and tolerability were judged better by physician as compared with patients' assessment. CONCLUSION: In this clinical trial, a topical cleansing product containing glycolic acid with pH 4 improved mild acne significantly following twice-daily application for 6 weeks as monotherapy.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Acné Vulgar / Detergentes / Glicolatos Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Cosmet Dermatol Asunto de la revista: DERMATOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Acné Vulgar / Detergentes / Glicolatos Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Cosmet Dermatol Asunto de la revista: DERMATOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Alemania