A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-&#945;.

Eurlings, Irene M J; Dentener, Mieke A; Mercken, Evi M; de Cabo, Rafael; Bracke, Ken R; Vernooy, Juanita H J; Wouters, Emiel F M; Reynaert, Niki L

A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.

Eurlings, Irene M J; Dentener, Mieke A; Mercken, Evi M; de Cabo, Rafael; Bracke, Ken R; Vernooy, Juanita H J; Wouters, Emiel F M; Reynaert, Niki L.

Afiliación

Eurlings IM; Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands; irene.eurlings@maastrichtuniversity.nl.
Dentener MA; Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands;
Mercken EM; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; and.
de Cabo R; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; and.
Bracke KR; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
Vernooy JH; Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands;
Wouters EF; Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands;
Reynaert NL; Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands;

Am J Physiol Lung Cell Mol Physiol ; 307(7): L557-65, 2014 Oct 01.

Article en En | MEDLINE | ID: mdl-25106431

Asunto(s)

Matriz Extracelular/metabolismo; Enfermedad Pulmonar Obstructiva Crónica/metabolismo; Factor de Necrosis Tumoral alfa/fisiología; Remodelación de las Vías Aéreas (Respiratorias)/inmunología; Animales; Modelos Animales de Enfermedad; Elastina/metabolismo; Matriz Extracelular/patología; Colágenos Fibrilares/metabolismo; Expresión Génica; Ácido Hialurónico/metabolismo; Lipopolisacáridos/farmacología; Masculino; Metaloproteinasa 2 de la Matriz/genética; Metaloproteinasa 2 de la Matriz/metabolismo; Metaloproteinasa 9 de la Matriz/genética; Metaloproteinasa 9 de la Matriz/metabolismo; Ratones; Ratones Endogámicos C57BL; Alveolos Pulmonares/inmunología; Alveolos Pulmonares/metabolismo; Alveolos Pulmonares/patología; Enfermedad Pulmonar Obstructiva Crónica/etiología; Enfermedad Pulmonar Obstructiva Crónica/inmunología; Fumar/efectos adversos

Palabras clave

chronic obstructive pulmonary disease; elastin; mice model; tumor necrosis factor-α

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor de Necrosis Tumoral alfa / Enfermedad Pulmonar Obstructiva Crónica / Matriz Extracelular Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Asunto de la revista: BIOLOGIA MOLECULAR / FISIOLOGIA Año: 2014 Tipo del documento: Article

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