Activating transcription factor 3-mediated chemo-intervention with cancer chemokines in a noncanonical pathway under endoplasmic reticulum stress.

Park, Seong-Hwan; Kim, Juil; Do, Kee Hun; Park, Jiyeon; Oh, Chang Gyu; Choi, Hye Jin; Song, Bo Gyoung; Lee, Seung Joon; Kim, Yong Sik; Moon, Yuseok

Park, Seong-Hwan; Kim, Juil; Do, Kee Hun; Park, Jiyeon; Oh, Chang Gyu; Choi, Hye Jin; Song, Bo Gyoung; Lee, Seung Joon; Kim, Yong Sik; Moon, Yuseok.

Afiliación

Park SH; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea,; Research Institute for Basic Sciences and Medical Research Institute, Pusan National University, Busan 609-735, Korea.
Kim J; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea.
Do KH; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea.
Park J; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea.
Oh CG; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea.
Choi HJ; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea.
Song BG; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea.
Lee SJ; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea.
Kim YS; Department of Pharmacology, College of Medicine, Seoul National University, Seoul 110-799, Korea, and.
Moon Y; Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan 626-870, Korea,; Research Institute for Basic Sciences and Medical Research Institute, Pusan National University, Busan 609-735, Korea,; Immunoregulatory Therape

J Biol Chem ; 289(39): 27118-27133, 2014 Sep 26.

Article en En | MEDLINE | ID: mdl-25122760

Asunto(s)

Factor de Transcripción Activador 3/metabolismo; Quimiocinas/biosíntesis; Estrés del Retículo Endoplásmico; Regulación Neoplásica de la Expresión Génica; Proteínas de Neoplasias/metabolismo; Neoplasias/metabolismo; Transducción de Señal; Factor de Transcripción Activador 3/genética; Animales; Línea Celular Tumoral; Quimiocinas/genética; Proteínas ELAV/genética; Proteínas ELAV/metabolismo; Proteína 1 Similar a ELAV; Proteína 1 de la Respuesta de Crecimiento Precoz/genética; Proteína 1 de la Respuesta de Crecimiento Precoz/metabolismo; Epigénesis Genética/genética; Humanos; Ratones; FN-kappa B/genética; FN-kappa B/metabolismo; Proteínas de Neoplasias/genética; Neoplasias/genética; Neoplasias/patología; Estabilidad Proteica; Proteínas Represoras/genética; Proteínas Represoras/metabolismo

Palabras clave

ATF3; Apigenin; Cancer Chemoprevention; Chemokine; ER Stress; Early Growth Response Protein 1 (EGR-1); Intestinal Cancer Cells; NF-kB Transcription Factor

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Regulación Neoplásica de la Expresión Génica / Quimiocinas / Factor de Transcripción Activador 3 / Estrés del Retículo Endoplásmico / Proteínas de Neoplasias / Neoplasias Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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