Stable isotope labeling by amino acids in cell culture-based liquid chromatography-mass spectrometry assay to measure microtubule dynamics in neuronal cell cultures.

Polson, Craig; Cantone, Joseph L; Wei, Cong; Drexler, Dieter M; Meredith, Jere E

Polson, Craig; Cantone, Joseph L; Wei, Cong; Drexler, Dieter M; Meredith, Jere E.

Afiliación

Polson C; Neuroscience Biology, Bristol-Myers Squibb Research and Development, Wallingford, CT 06492, USA.
Cantone JL; Pharmaceutical Candidate Optimization-Discovery Analytical Sciences, Bristol-Myers Squibb Research and Development, Wallingford, CT 06492, USA.
Wei C; Pharmaceutical Candidate Optimization-Discovery Analytical Sciences, Bristol-Myers Squibb Research and Development, Wallingford, CT 06492, USA.
Drexler DM; Pharmaceutical Candidate Optimization-Discovery Analytical Sciences, Bristol-Myers Squibb Research and Development, Wallingford, CT 06492, USA.
Meredith JE; Neuroscience Biology, Bristol-Myers Squibb Research and Development, Wallingford, CT 06492, USA. Electronic address: jere.meredith@bms.com.

Anal Biochem ; 466: 65-71, 2014 Dec 01.

Article en En | MEDLINE | ID: mdl-25175011

Asunto(s)

Bioensayo/métodos; Marcaje Isotópico/métodos; Microtúbulos/metabolismo; Neuronas/metabolismo; Animales; Encéfalo/citología; Técnicas de Cultivo de Célula; Cromatografía Liquida; Espectrometría de Masas; Neuronas/citología; Péptidos/química; Ratas; Reproducibilidad de los Resultados

Palabras clave

LCMS; Microtubule; Neurons; SILAC; Tubulin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bioensayo / Marcaje Isotópico / Microtúbulos / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Anal Biochem Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

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