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A population pharmacokinetic modeling approach shows that serum penicillin G concentrations are below inhibitory concentrations by two weeks after benzathine penicillin G injection in the majority of young adults.
Neely, Michael; Kaplan, Edward L; Blumer, Jeffrey L; Faix, Dennis J; Broderick, Michael P.
Afiliación
  • Neely M; Laboratory of Applied Pharmacokinetics and Bioinformatics, Children's Hospital of Los Angeles, and Keck School of Medicine of USC, Los Angeles, California, USA mneely@usc.edu.
  • Kaplan EL; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
  • Blumer JL; Departments of Pediatrics and Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Faix DJ; Operational Infectious Diseases Department, Naval Health Research Center, San Diego, California, USA.
  • Broderick MP; Operational Infectious Diseases Department, Naval Health Research Center, San Diego, California, USA.
Antimicrob Agents Chemother ; 58(11): 6735-41, 2014 Nov.
Article en En | MEDLINE | ID: mdl-25182635
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Penicilina G Benzatina / Streptococcus pyogenes / Antibacterianos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Humans / Male Idioma: En Revista: Antimicrob Agents Chemother Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Penicilina G Benzatina / Streptococcus pyogenes / Antibacterianos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Humans / Male Idioma: En Revista: Antimicrob Agents Chemother Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos