Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with &#945;6ß4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival.

Wang, Haiyao; Jin, Haining; Beauvais, DeannaLee M; Rapraeger, Alan C

Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6ß4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival.

Wang, Haiyao; Jin, Haining; Beauvais, DeannaLee M; Rapraeger, Alan C.

Afiliación

Wang H; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Jin H; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Beauvais DM; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Rapraeger AC; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin 53705; Carbone Cancer Center, Wisconsin Institutes for Medical Research, University of Wisconsin-Madison, Madison, Wisconsin 53705. Electronic address: rapraeger@humonc.wisc.edu.

J Biol Chem ; 289(44): 30318-30332, 2014 Oct 31.

Article en En | MEDLINE | ID: mdl-25202019

Asunto(s)

Movimiento Celular; Supervivencia Celular; Integrina alfa6beta4/metabolismo; Sindecano-1/metabolismo; Sindecano-4/metabolismo; Secuencia de Aminoácidos; Moléculas de Adhesión Celular/metabolismo; Línea Celular Tumoral; Citoplasma/metabolismo; Receptores ErbB/metabolismo; Receptores ErbB/fisiología; Humanos; Integrina alfa6beta4/química; Integrina alfa6beta4/genética; Datos de Secuencia Molecular; Mutación Missense; Unión Proteica; Dominios y Motivos de Interacción de Proteínas; Receptor ErbB-2/fisiología; Transducción de Señal; Sindecano-1/química; Sindecano-4/química; Kalinina

Palabras clave

Carcinogenesis; Cell Invasion; Epidermal Growth Factor Receptor (EGFR); Integrin; Laminin; Syndecan; Wound Healing

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Movimiento Celular / Supervivencia Celular / Integrina alfa6beta4 / Sindecano-1 / Sindecano-4 Límite: Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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