Multifunctional liposomes reduce brain ß-amyloid burden and ameliorate memory impairment in Alzheimer's disease mouse models.

Balducci, Claudia; Mancini, Simona; Minniti, Stefania; La Vitola, Pietro; Zotti, Margherita; Sancini, Giulio; Mauri, Mario; Cagnotto, Alfredo; Colombo, Laura; Fiordaliso, Fabio; Grigoli, Emanuele; Salmona, Mario; Snellman, Anniina; Haaparanta-Solin, Merja; Forloni, Gianluigi; Masserini, Massimo; Re, Francesca

Balducci, Claudia; Mancini, Simona; Minniti, Stefania; La Vitola, Pietro; Zotti, Margherita; Sancini, Giulio; Mauri, Mario; Cagnotto, Alfredo; Colombo, Laura; Fiordaliso, Fabio; Grigoli, Emanuele; Salmona, Mario; Snellman, Anniina; Haaparanta-Solin, Merja; Forloni, Gianluigi; Masserini, Massimo; Re, Francesca.

Afiliación

Balducci C; Departments of Neuroscience.
Mancini S; Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy, and.
Minniti S; Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy, and.
La Vitola P; Departments of Neuroscience.
Zotti M; Departments of Neuroscience.
Sancini G; Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy, and.
Mauri M; Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy, and.
Cagnotto A; Molecular Biochemistry and Pharmacology, and.
Colombo L; Molecular Biochemistry and Pharmacology, and.
Fiordaliso F; Cardiovascular Research, Institute for Istituto di Ricovero e Cura a Carattere Scientifico/Mario Negri Institute for Pharmacological Research, 20156 Milan, Italy.
Grigoli E; Departments of Neuroscience.
Salmona M; Molecular Biochemistry and Pharmacology, and.
Snellman A; MediCity/PET Preclinical Laboratory, Turku PET Centre, University of Turku, 20520 Turku, Finland.
Haaparanta-Solin M; MediCity/PET Preclinical Laboratory, Turku PET Centre, University of Turku, 20520 Turku, Finland.
Forloni G; Departments of Neuroscience.
Masserini M; Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy, and massimo.masserini@unimib.it.
Re F; Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy, and.

J Neurosci ; 34(42): 14022-31, 2014 Oct 15.

Article en En | MEDLINE | ID: mdl-25319699

Asunto(s)

Enfermedad de Alzheimer/tratamiento farmacológico; Apolipoproteínas E/administración & dosificación; Modelos Animales de Enfermedad; Liposomas/administración & dosificación; Trastornos de la Memoria/tratamiento farmacológico; Placa Amiloide/tratamiento farmacológico; Enfermedad de Alzheimer/metabolismo; Enfermedad de Alzheimer/patología; Péptidos beta-Amiloides/antagonistas & inhibidores; Péptidos beta-Amiloides/metabolismo; Animales; Apolipoproteínas E/metabolismo; Liposomas/metabolismo; Masculino; Trastornos de la Memoria/metabolismo; Trastornos de la Memoria/patología; Ratones; Ratones Endogámicos BALB C; Ratones Endogámicos C57BL; Ratones Transgénicos; Fragmentos de Péptidos/antagonistas & inhibidores; Fragmentos de Péptidos/metabolismo; Placa Amiloide/metabolismo; Placa Amiloide/patología; Distribución Aleatoria

Palabras clave

Abeta; Alzheimer; cognitive impairment; liposomes; nanomedicine; oligomers

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Apolipoproteínas E / Placa Amiloide / Modelos Animales de Enfermedad / Enfermedad de Alzheimer / Liposomas / Trastornos de la Memoria Límite: Animals Idioma: En Revista: J Neurosci Año: 2014 Tipo del documento: Article

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