Activin upregulation by NF-&#954;B is required to maintain mesenchymal features of cancer stem-like cells in non-small cell lung cancer.

Wamsley, J Jacob; Kumar, Manish; Allison, David F; Clift, Sheena H; Holzknecht, Caitlyn M; Szymura, Szymon J; Hoang, Stephen A; Xu, Xiaojiang; Moskaluk, Christopher A; Jones, David R; Bekiranov, Stefan; Mayo, Marty W

Activin upregulation by NF-κB is required to maintain mesenchymal features of cancer stem-like cells in non-small cell lung cancer.

Wamsley, J Jacob; Kumar, Manish; Allison, David F; Clift, Sheena H; Holzknecht, Caitlyn M; Szymura, Szymon J; Hoang, Stephen A; Xu, Xiaojiang; Moskaluk, Christopher A; Jones, David R; Bekiranov, Stefan; Mayo, Marty W.

Afiliación

Wamsley JJ; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Kumar M; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Allison DF; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Clift SH; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Holzknecht CM; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Szymura SJ; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Hoang SA; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Xu X; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Moskaluk CA; Department of Pathology, University of Virginia, Charlottesville, Virginia.
Jones DR; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia. Department of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Bekiranov S; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia.
Mayo MW; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia. mwm3y@virginia.edu sb3de@Virginia.edu.

Cancer Res ; 75(2): 426-35, 2015 Jan 15.

Article en En | MEDLINE | ID: mdl-25432175

Asunto(s)

Activinas/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/patología; Neoplasias Pulmonares/patología; FN-kappa B/metabolismo; Células Madre Neoplásicas/patología; Carcinoma de Pulmón de Células no Pequeñas/genética; Carcinoma de Pulmón de Células no Pequeñas/metabolismo; Línea Celular Tumoral; Transición Epitelial-Mesenquimal; Humanos; Subunidades beta de Inhibinas/metabolismo; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Mesodermo/metabolismo; Mesodermo/patología; Células Madre Neoplásicas/metabolismo; ARN Neoplásico/biosíntesis; ARN Neoplásico/genética; Esferoides Celulares; Regulación hacia Arriba

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / FN-kappa B / Carcinoma de Pulmón de Células no Pequeñas / Activinas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Res Año: 2015 Tipo del documento: Article

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