Mortality in women with pregnancy-associated malignant melanoma.
J Am Acad Dermatol
; 71(6): 1093-101, 2014 Dec.
Article
en En
| MEDLINE
| ID: mdl-25440438
ABSTRACT
BACKGROUND:
Malignant melanoma (MM) is one of the most common malignancies in young women. It remains debated whether a MM diagnosed during pregnancy or lactation has a worse prognosis.OBJECTIVE:
We sought to examine mortality in women with pregnancy-associated MM (PAMM) (diagnosed during pregnancy and up to 2-years postpartum).METHODS:
This was a population-based cohort study based on information retrieved from the Swedish Cancer and Multi-Generation Registers. Hazard ratios with 95% confidence intervals adjusted for age, period, education, parity, and tumor location were estimated.RESULTS:
In total, 6857 women and girls aged 15 to 44 years with a diagnosis of cutaneous MM between 1963 and 2009 were identified. Of these, 1019 cases were classified as PAMM. The cause-specific mortality did not differ between PAMM and MM not diagnosed near childbirth (adjusted hazard ratio 1.09, 95% confidence interval 0.83-1.42).LIMITATIONS:
Information on stage at diagnosis was available only for a subset of patientsCONCLUSION:
Overall, the cause-specific mortality in women and girls with PAMM did not differ from that in women and girls with non-PAMM. The current findings do not provide evidence of an adverse prognostic influence of pregnancy or a recent birth.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Complicaciones Neoplásicas del Embarazo
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Neoplasias Cutáneas
/
Melanoma
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Pregnancy
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Am Acad Dermatol
Año:
2014
Tipo del documento:
Article