The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor Î³ requires G protein pathway suppressor 2.

Guo, Chun; Li, Yali; Gow, Chien-Hung; Wong, Madeline; Zha, Jikun; Yan, Chunxia; Liu, Hongqi; Wang, Yongjun; Burris, Thomas P; Zhang, Jinsong

Guo, Chun; Li, Yali; Gow, Chien-Hung; Wong, Madeline; Zha, Jikun; Yan, Chunxia; Liu, Hongqi; Wang, Yongjun; Burris, Thomas P; Zhang, Jinsong.

Afiliación

Guo C; From the Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, St. Louis, Missouri 63104, the Department of Cancer Biology, Vontz Center for Molecular Studies, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.
Li Y; the Department of Cancer Biology, Vontz Center for Molecular Studies, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.
Gow CH; the Department of Cancer Biology, Vontz Center for Molecular Studies, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, the Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City 220, Taiwan.
Wong M; From the Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, St. Louis, Missouri 63104.
Zha J; From the Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, St. Louis, Missouri 63104.
Yan C; the Department of Cancer Biology, Vontz Center for Molecular Studies, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, the College of Medicine and Forensics, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710049, China, and.
Liu H; the Infection and Immunity Research Group, Institute of Medical Biology, Chinese Academy of Medical Science, Peking Union Medical College, Kunming, Yunnan 650018, China.
Wang Y; From the Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, St. Louis, Missouri 63104.
Burris TP; From the Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, St. Louis, Missouri 63104.
Zhang J; From the Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, St. Louis, Missouri 63104, the Department of Cancer Biology, Vontz Center for Molecular Studies, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, jinsongzhang@slu.edu.

J Biol Chem ; 290(6): 3666-79, 2015 Feb 06.

Article en En | MEDLINE | ID: mdl-25519902

Asunto(s)

Péptidos y Proteínas de Señalización Intracelular/metabolismo; Co-Represor 1 de Receptor Nuclear/metabolismo; PPAR gamma/genética; Activación Transcripcional; Adipogénesis; Secuencia de Aminoácidos; Animales; Línea Celular; Células Madre Embrionarias/citología; Células Madre Embrionarias/metabolismo; Fibroblastos/citología; Fibroblastos/metabolismo; Péptidos y Proteínas de Señalización Intracelular/genética; Ratones; Datos de Secuencia Molecular; Mutación; Co-Represor 1 de Receptor Nuclear/genética; PPAR gamma/química; PPAR gamma/metabolismo; Unión Proteica; Conformación Proteica; Receptores alfa de Hormona Tiroidea/metabolismo

Palabras clave

Conformational Change; GPS2; NCoR; Nuclear Receptor; PPARÎ³; Peroxisome Proliferator-Activated Receptor (PPAR); Thyroid Hormone; Transcription Coactivator; Transcription Corepressor; Transcriptional Repression

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Activación Transcripcional / Péptidos y Proteínas de Señalización Intracelular / PPAR gamma / Co-Represor 1 de Receptor Nuclear Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article

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