Urban air and tobacco smoke as conditions that increase the risk of oxidative stress and respiratory response in youth.
Environ Res
; 137: 141-6, 2015 Feb.
Article
en En
| MEDLINE
| ID: mdl-25531819
ABSTRACT
BACKGROUND:
Air pollution and tobacco smoke can induce negative effects on the human health and often leads to the formation of oxidative stress.OBJECTIVE:
The purpose of this study was to clarify the role of the urbanization degree and of passive exposure to tobacco smoke in the formation of oxidative stress. Thus, a group of non-smoking adolescents was recruited among those who live and attend school in areas with three different population densities. To each subject a spot of urine was collected to quantify 15-F2t isoprostane as a marker of oxidative stress and cotinine as a marker of passive exposure to tobacco smoke. Furthermore, respiratory functionality was also measured.RESULTS:
Multiple linear regression analysis results showed a direct correlation (p<0.0001) of 15-F2t isoprostane with both the urbanization and passive smoke. Lung function parameters proved significantly lower for the subjects living in the most populous city of Torino.CONCLUSION:
This remarks the negative effect that urbanization has on the respiratory conditions. Lastly, lung functionality presented a low inverse correlation with 15-F2t isoprostane, suggesting an independent mechanism than that of the urban factor.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Contaminación por Humo de Tabaco
/
Cotinina
/
Isoprostanos
/
Exposición a Riesgos Ambientales
/
Pulmón
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Environ Res
Año:
2015
Tipo del documento:
Article