The distinct genetic pattern of ALS in Turkey and novel mutations.

Özoguz, Aslihan; Uyan, Özgün; Birdal, Günes; Iskender, Ceren; Kartal, Ece; Lahut, Suna; Ömür, Özgür; Agim, Zeynep Sena; Eken, Asli Gündogdu; Sen, Nesli Ece; Kavak, Pinar; Saygi, Ceren; Sapp, Peter C; Keagle, Pamela; Parman, Yesim; Tan, Ersin; Koç, Filiz; Deymeer, Feza; Oflazer, Piraye; Hanagasi, Hasmet; Gürvit, Hakan; Bilgiç, Basar; Durmus, Hacer; Ertas, Mustafa; Kotan, Dilcan; Akalin, Mehmet Ali; Güllüoglu, Halil; Zarifoglu, Mehmet; Aysal, Fikret; Dösoglu, Nilgün; Bilguvar, Kaya; Günel, Murat; Keskin, Özlem; Akgün, Tahsin; Özçelik, Hilmi; Landers, John E; Brown, Robert H; Basak, A Nazli

Özoguz, Aslihan; Uyan, Özgün; Birdal, Günes; Iskender, Ceren; Kartal, Ece; Lahut, Suna; Ömür, Özgür; Agim, Zeynep Sena; Eken, Asli Gündogdu; Sen, Nesli Ece; Kavak, Pinar; Saygi, Ceren; Sapp, Peter C; Keagle, Pamela; Parman, Yesim; Tan, Ersin; Koç, Filiz; Deymeer, Feza; Oflazer, Piraye; Hanagasi, Hasmet; Gürvit, Hakan; Bilgiç, Basar; Durmus, Hacer; Ertas, Mustafa; Kotan, Dilcan; Akalin, Mehmet Ali; Güllüoglu, Halil; Zarifoglu, Mehmet; Aysal, Fikret; Dösoglu, Nilgün; Bilguvar, Kaya; Günel, Murat; Keskin, Özlem; Akgün, Tahsin; Özçelik, Hilmi; Landers, John E; Brown, Robert H; Basak, A Nazli.

Afiliación

Özoguz A; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Uyan Ö; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Birdal G; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Iskender C; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Kartal E; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Lahut S; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Ömür Ö; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Agim ZS; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Eken AG; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Sen NE; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Kavak P; Computer Engineering Department, Bogaziçi University, Istanbul, Turkey.
Saygi C; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey.
Sapp PC; Neurology Department, Medical School, University of Massachusetts, Worcester, MA, USA.
Keagle P; Neurology Department, Medical School, University of Massachusetts, Worcester, MA, USA.
Parman Y; Neurology Department, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Tan E; Neurology Department, Medical School, Hacettepe University, Ankara, Turkey.
Koç F; Neurology Department, Medical School, Çukurova University, Adana, Turkey.
Deymeer F; Neurology Department, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Oflazer P; Neurology Department, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Hanagasi H; Neurology Department, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Gürvit H; Neurology Department, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Bilgiç B; Neurology Department, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Durmus H; Neurology Department, Istanbul Medical School, Istanbul University, Istanbul, Turkey.
Ertas M; Department of Neurology, Liv Hospital, Istanbul, Turkey.
Kotan D; Faculty of Medicine, Department of Neurology, Sakarya University, Sakarya, Turkey.
Akalin MA; Neurology Department, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
Güllüoglu H; Department of Neurology, Medical Park Izmir Hospital, Izmir, Turkey.
Zarifoglu M; Department of Neurology, School of Medicine, Uludag University, Bursa, Turkey.
Aysal F; Bakirköy Research and Training Hospital for Neurologic and Psychiatric Diseases, Istanbul, Turkey.
Dösoglu N; Department of Microbiology, Haydarpasa Numune Education and Research Hospital, Istanbul, Turkey.
Bilguvar K; Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Günel M; Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Keskin Ö; Chemical and Biological Engineering Department, Koç University, Istanbul, Turkey.
Akgün T; Department of Anesthesiology and Reanimation, American Hospital, Istanbul, Turkey.
Özçelik H; Department of Pathology and Laboratory Medicine, Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Ontario, Canada.
Landers JE; Neurology Department, Medical School, University of Massachusetts, Worcester, MA, USA.
Brown RH; Neurology Department, Medical School, University of Massachusetts, Worcester, MA, USA.
Basak AN; Suna and Inan Kiraç Foundation, Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Bogaziçi University, Istanbul, Turkey. Electronic address: basak@boun.edu.tr.

Neurobiol Aging ; 36(4): 1764.e9-1764.e18, 2015 Apr.

Article en En | MEDLINE | ID: mdl-25681989

Asunto(s)

Esclerosis Amiotrófica Lateral/genética; Estudios de Asociación Genética; Mutación/genética; Proteínas/genética; Proteína FUS de Unión a ARN/genética; Superóxido Dismutasa/genética; Proteínas Adaptadoras Transductoras de Señales/genética; Adolescente; Adulto; Anciano; Proteínas Relacionadas con la Autofagia; Proteína C9orf72; Proteínas de Ciclo Celular/genética; Proteínas del Citoesqueleto; Proteínas de Unión al ADN/genética; Exoma/genética; Femenino; Factores de Intercambio de Guanina Nucleótido/genética; Humanos; Péptidos y Proteínas de Señalización Intracelular/genética; Masculino; Proteínas de Transporte de Membrana; Persona de Mediana Edad; Proteínas del Tejido Nervioso/genética; Proteínas Nucleares/genética; Proteínas Oncogénicas/genética; Proteína Desglicasa DJ-1; Proteínas Serina-Treonina Quinasas/genética; Proteína Sequestosoma-1; Superóxido Dismutasa-1; Canales Catiónicos TRPM/genética; Factor de Transcripción TFIIIA/genética; Turquía; Ubiquitinas/genética; Adulto Joven

Palabras clave

ALS; C9orf72; FUS; SOD1; TDP-43; Turkey

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Superóxido Dismutasa / Proteínas / Proteína FUS de Unión a ARN / Estudios de Asociación Genética / Esclerosis Amiotrófica Lateral / Mutación Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Neurobiol Aging Año: 2015 Tipo del documento: Article País de afiliación: Turquía

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