Urinary extracellular vesicles as reservoirs of altered proteins during the pathogenesis of polycystic kidney disease.

Pocsfalvi, Gabriella; Raj, Delfin A A; Fiume, Immacolata; Vilasi, Annalisa; Trepiccione, Francesco; Capasso, Giovambattista

Pocsfalvi, Gabriella; Raj, Delfin A A; Fiume, Immacolata; Vilasi, Annalisa; Trepiccione, Francesco; Capasso, Giovambattista.

Afiliación

Pocsfalvi G; Mass Spectrometry and Proteomics, Institute of Biosciences and BioResources, National Research Council of Italy, Naples, Italy.
Raj DA; Mass Spectrometry and Proteomics, Institute of Biosciences and BioResources, National Research Council of Italy, Naples, Italy.
Fiume I; Mass Spectrometry and Proteomics, Institute of Biosciences and BioResources, National Research Council of Italy, Naples, Italy.
Vilasi A; Mass Spectrometry and Proteomics, Institute of Biosciences and BioResources, National Research Council of Italy, Naples, Italy.
Trepiccione F; Division of Nephrology, Department of Cardio-Vascular Sciences, Second University of Naples, Naples, Italy.
Capasso G; Division of Nephrology, Department of Cardio-Vascular Sciences, Second University of Naples, Naples, Italy.

Proteomics Clin Appl ; 9(5-6): 552-67, 2015 Jun.

Article en En | MEDLINE | ID: mdl-25755179

Asunto(s)

Vesículas Extracelulares/metabolismo; Enfermedades Renales Poliquísticas/orina; Adulto; Anciano; Antagonistas de los Receptores de Hormonas Antidiuréticas/farmacología; Antagonistas de los Receptores de Hormonas Antidiuréticas/uso terapéutico; Acuaporina 2/orina; Benzazepinas/farmacología; Benzazepinas/uso terapéutico; Biomarcadores/orina; Proteínas de Unión al Calcio/orina; Estudios de Casos y Controles; Humanos; Masculino; Persona de Mediana Edad; Enfermedades Renales Poliquísticas/tratamiento farmacológico; Proteoma/metabolismo; Tolvaptán; Vía de Señalización Wnt; Adulto Joven

Palabras clave

Ciliary signaling pathway; Extracellular vesicles; Kidney physiology; Polycystic kidney disease; Quantitative proteomics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vesículas Extracelulares / Enfermedades Renales Poliquísticas Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Límite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Proteomics Clin Appl Asunto de la revista: BIOQUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Italia

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