Investigation of the conformational dynamics of the apo A2A adenosine receptor.

Caliman, Alisha D; Swift, Sara E; Wang, Yi; Miao, Yinglong; McCammon, J Andrew

Caliman, Alisha D; Swift, Sara E; Wang, Yi; Miao, Yinglong; McCammon, J Andrew.

Afiliación

Caliman AD; Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093.
Swift SE; Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093.
Wang Y; Howard Hughes Medical Institute, University of California at San Diego, La Jolla, California, 92093.
Miao Y; Howard Hughes Medical Institute, University of California at San Diego, La Jolla, California, 92093.
McCammon JA; Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093.

Protein Sci ; 24(6): 1004-12, 2015 Jun.

Article en En | MEDLINE | ID: mdl-25761901

Asunto(s)

Receptor de Adenosina A2A/química; Receptor de Adenosina A2A/metabolismo; Simulación por Computador; Humanos; Enlace de Hidrógeno; Simulación de Dinámica Molecular; Conformación Proteica

Palabras clave

GPCR; NPxxY; activation; adenosine A2A; molecular dynamics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptor de Adenosina A2A Límite: Humans Idioma: En Revista: Protein Sci Asunto de la revista: BIOQUIMICA Año: 2015 Tipo del documento: Article

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