CD200R1 agonist attenuates LPS-induced inflammatory response in human renal proximal tubular epithelial cells by regulating TLR4-MyD88-TAK1-mediated NF-&#954;B and MAPK pathway.

Ding, Yan; Yang, Huilan; Xiang, Wei; He, Xiaojie; Liao, Wang; Yi, Zhuwen

CD200R1 agonist attenuates LPS-induced inflammatory response in human renal proximal tubular epithelial cells by regulating TLR4-MyD88-TAK1-mediated NF-κB and MAPK pathway.

Ding, Yan; Yang, Huilan; Xiang, Wei; He, Xiaojie; Liao, Wang; Yi, Zhuwen.

Afiliación

Ding Y; Department of Dermatology, Maternal and Child Health Care Hospital of Hainan Province, Haikou 570206, China; Department of Cardiology, Hainan General Hospital, Haikou 570102, China.
Yang H; Department of Dermatology, General Hospital of Guangzhou Military Command of PLA, Southern Medical University, Guangzhou 510010, China. Electronic address: yanghuilangz@163.com.
Xiang W; Department of Dermatology, Maternal and Child Health Care Hospital of Hainan Province, Haikou 570206, China. Electronic address: xiangweihn2@163.com.
He X; Department of Nephropathy, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha 410000, China.
Liao W; Department of Cardiology, Hainan General Hospital, Haikou 570102, China.
Yi Z; Department of Nephropathy, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha 410000, China.

Biochem Biophys Res Commun ; 460(2): 287-94, 2015 May 01.

Article en En | MEDLINE | ID: mdl-25791482

Asunto(s)

Inflamación/prevención & control; Túbulos Renales Proximales/efectos de los fármacos; Lipopolisacáridos/farmacología; Sistema de Señalización de MAP Quinasas; FN-kappa B/metabolismo; Receptores de Superficie Celular/agonistas; Antígenos de Superficie; Células Cultivadas; Células Epiteliales/metabolismo; Humanos; Inflamación/metabolismo; Túbulos Renales Proximales/enzimología; Túbulos Renales Proximales/metabolismo; Quinasas Quinasa Quinasa PAM/metabolismo; Factor 88 de Diferenciación Mieloide/metabolismo; Receptores de Orexina; Receptor Toll-Like 4/metabolismo

Palabras clave

CD200Fc; Human renal proximal tubular epithelial cells; Inflammation; MAPK; NF-κB; TLR4

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Lipopolisacáridos / FN-kappa B / Receptores de Superficie Celular / Sistema de Señalización de MAP Quinasas / Inflamación / Túbulos Renales Proximales Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2015 Tipo del documento: Article País de afiliación: China

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