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Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1.
Li, Xianjing; Wang, Duowei; Chen, Zhen; Lu, Ermei; Wang, Zhuo; Duan, Jingjing; Tian, Wei; Wang, Yun; You, Linjun; Zou, Yulian; Cheng, Yan; Zhu, Qingyi; Wan, Xiaojian; Xi, Tao; Jiang, Meisheng; Han, Yuyuan; Cao, Cong; Birnbaumer, Lutz; Chu, Wen-Ming; Yang, Yong.
Afiliación
  • Li X; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Wang D; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Chen Z; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Lu E; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Wang Z; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Duan J; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Tian W; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Wang Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • You L; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Zou Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Cheng Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Zhu Q; Department of Urology, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029, China;
  • Wan X; Department of Anesthesiology and Intensive Care Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China; and.
  • Xi T; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, Nanjing 211198, China;
  • Jiang M; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095;
  • Han Y; Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912
  • Cao C; Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912
  • Birnbaumer L; Laboratory of Neurobiology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 yy@cpu.edu.cn birbau1@gmail.com.
  • Chu WM; Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912
  • Yang Y; University of Hawaii Cancer Center, Honolulu, HI 96813
Proc Natl Acad Sci U S A ; 112(15): 4731-6, 2015 04 14.
Article en En | MEDLINE | ID: mdl-25825741
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfoproteínas / Receptores de Lipopolisacáridos / Subunidades alfa de la Proteína de Unión al GTP Gi-Go / Macrófagos Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfoproteínas / Receptores de Lipopolisacáridos / Subunidades alfa de la Proteína de Unión al GTP Gi-Go / Macrófagos Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article