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Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice.
Oyeniran, Clement; Sturgill, Jamie L; Hait, Nitai C; Huang, Wei-Ching; Avni, Dorit; Maceyka, Michael; Newton, Jason; Allegood, Jeremy C; Montpetit, Alison; Conrad, Daniel H; Milstien, Sheldon; Spiegel, Sarah.
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  • Oyeniran C; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Sturgill JL; Department of Microbiology & Immunology, Virginia Commonwealth University School of Medicine, Richmond, Va; School of Nursing, Virginia Commonwealth University, Richmond, Va.
  • Hait NC; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Huang WC; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Avni D; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Maceyka M; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Newton J; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Allegood JC; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Montpetit A; School of Nursing, Virginia Commonwealth University, Richmond, Va.
  • Conrad DH; Department of Microbiology & Immunology, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Milstien S; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va.
  • Spiegel S; Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, Va. Electronic address: sspiegel@vcu.edu.
J Allergy Clin Immunol ; 136(4): 1035-46.e6, 2015 Oct.
Article en En | MEDLINE | ID: mdl-25842287
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Asma / Ceramidas / Regulación de la Expresión Génica / Homeostasis / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: J Allergy Clin Immunol Año: 2015 Tipo del documento: Article País de afiliación: Ciudad del Vaticano
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Asma / Ceramidas / Regulación de la Expresión Génica / Homeostasis / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: J Allergy Clin Immunol Año: 2015 Tipo del documento: Article País de afiliación: Ciudad del Vaticano