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Aspartate-modified doxorubicin on its N-terminal increases drug accumulation in LAT1-overexpressing tumors.
Wu, Weidang; Dong, Yan; Gao, Jing; Gong, Min; Zhang, Xing; Kong, Weiling; Li, Yazhuo; Zeng, Yong; Si, Duanyun; Wei, Zihong; Ci, Xiaoyan; Jiang, Lixin; Li, Wei; Li, Quansheng; Yi, Xiulin; Liu, Changxiao.
Afiliación
  • Wu W; School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.
  • Dong Y; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Gao J; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Gong M; Tianjin Medical University, Tianjin, China.
  • Zhang X; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Kong W; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Li Y; Tianjin University of Traditional Chinese Medicine, Tianjin, China.
  • Zeng Y; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Si D; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Wei Z; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Ci X; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Jiang L; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Li W; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Li Q; Hefei Tianmai Biotechnology Development Co., Ltd, Hefei, China.
  • Yi X; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
  • Liu C; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin, China.
Cancer Sci ; 106(6): 747-756, 2015 Jun.
Article en En | MEDLINE | ID: mdl-25867020
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Doxorrubicina / Ácido Aspártico / Transportador de Aminoácidos Neutros Grandes 1 / Antibióticos Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Cancer Sci Año: 2015 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Doxorrubicina / Ácido Aspártico / Transportador de Aminoácidos Neutros Grandes 1 / Antibióticos Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Cancer Sci Año: 2015 Tipo del documento: Article País de afiliación: China