Measuring propargyl-linked drug populations inside bacterial cells, and their interaction with a dihydrofolate reductase target, by Raman microscopy.

Heidari-Torkabadi, Hossein; Che, Tao; Lombardo, Michael N; Wright, Dennis L; Anderson, Amy C; Carey, Paul R

Heidari-Torkabadi, Hossein; Che, Tao; Lombardo, Michael N; Wright, Dennis L; Anderson, Amy C; Carey, Paul R.

Afiliación

Lombardo MN; §Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269, United States.
Wright DL; §Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269, United States.
Anderson AC; §Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269, United States.

Biochemistry ; 54(17): 2719-26, 2015 May 05.

Article en En | MEDLINE | ID: mdl-25871808

Asunto(s)

Escherichia coli/metabolismo; Antagonistas del Ácido Fólico/farmacocinética; Klebsiella pneumoniae/metabolismo; Microscopía/métodos; Espectrometría Raman/métodos; Staphylococcus aureus/metabolismo; Tetrahidrofolato Deshidrogenasa/metabolismo; Cristalografía por Rayos X; Tetrahidrofolato Deshidrogenasa/química

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Espectrometría Raman / Staphylococcus aureus / Tetrahidrofolato Deshidrogenasa / Escherichia coli / Antagonistas del Ácido Fólico / Klebsiella pneumoniae / Microscopía Idioma: En Revista: Biochemistry Año: 2015 Tipo del documento: Article

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