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Targeting HER2 aberrations as actionable drivers in lung cancers: phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors.
Kris, M G; Camidge, D R; Giaccone, G; Hida, T; Li, B T; O'Connell, J; Taylor, I; Zhang, H; Arcila, M E; Goldberg, Z; Jänne, P A.
Afiliación
  • Kris MG; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York krism@mskcc.org.
  • Camidge DR; Department of Medical Oncology, University of Colorado Denver, Aurora.
  • Giaccone G; Lombardi Cancer Center, Georgetown University, Washington, USA.
  • Hida T; Department of Thoracic Oncology, Aichi Cancer Center, Chikusa-ku Nagoya, Japan.
  • Li BT; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York.
  • O'Connell J; Pfizer Oncology, Pfizer, Inc., New York.
  • Taylor I; Translational Oncology, Pfizer, Inc., Groton, USA.
  • Zhang H; Pfizer (China) Research & Development Co. Ltd, Pfizer, Inc., Shanghai, China.
  • Arcila ME; Molecular Diagnostics Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York.
  • Goldberg Z; Pfizer Oncology, Pfizer, Inc., San Diego.
  • Jänne PA; Lowe Center for Thoracic Oncology and the Belfer Institute for Applied Cancer Science, Dana Farber Cancer Institute, Boston, USA.
Ann Oncol ; 26(7): 1421-7, 2015 Jul.
Article en En | MEDLINE | ID: mdl-25899785
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Amplificación de Genes / Carcinoma de Pulmón de Células no Pequeñas / Receptor ErbB-2 / Quinazolinonas / Mutación Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Amplificación de Genes / Carcinoma de Pulmón de Células no Pequeñas / Receptor ErbB-2 / Quinazolinonas / Mutación Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article