[Alteration of related transporters and its application significance in common intestinal disease, liver disease, renal disease and diabetes].
Yao Xue Xue Bao
; 50(2): 127-32, 2015 Feb.
Article
en Zh
| MEDLINE
| ID: mdl-25975017
ABSTRACT
Drug transporters are functional membrane proteins located in various tissues, which play vital roles in absorption, distribution and excretion of drugs, especially those located in intestine, liver and kidney. The expression and function of transporters will alter in diseases state, which affects the therapeutic effects of drugs by altering their pharmacokinetics. In this review, we focus on the alterations in related transporters and the effect on the drug therapy in common intestinal diseases, liver diseases, kidney diseases and diabetes mellitus.
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Banco de datos:
MEDLINE
Asunto principal:
Proteínas de Transporte de Membrana
/
Diabetes Mellitus
/
Enfermedades Intestinales
/
Enfermedades Renales
/
Hepatopatías
Límite:
Humans
Idioma:
Zh
Revista:
Yao Xue Xue Bao
Año:
2015
Tipo del documento:
Article