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A novel HPLC-MS/MS method for the simultaneous determination of astemizole and its major metabolite in dog or monkey plasma and application to pharmacokinetics.
Back, Hyun-moon; Lee, Jong-Hwa; Chae, Jung-woo; Song, Byungjeong; Seo, Joung-Wook; Yun, Hwi-yeol; Kwon, Kwang-il.
Afiliación
  • Back HM; College of Pharmacy, Chungnam National University, Daejeon 305-764, Republic of Korea.
  • Lee JH; General and Applied Toxicology Center, Korea Institute of Toxicology, Daejeon 305-600, Republic of Korea.
  • Chae JW; College of Pharmacy, Chungnam National University, Daejeon 305-764, Republic of Korea.
  • Song B; College of Pharmacy, Chungnam National University, Daejeon 305-764, Republic of Korea.
  • Seo JW; Research Center for Safety Pharmacology, Korea Institute of Toxicology, Daejeon 305-600, Republic of Korea.
  • Yun HY; College of Pharmacy, Chungnam National University, Daejeon 305-764, Republic of Korea.
  • Kwon KI; College of Pharmacy, Chungnam National University, Daejeon 305-764, Republic of Korea. Electronic address: kwon@cnu.ac.kr.
J Pharm Biomed Anal ; 114: 121-6, 2015 Oct 10.
Article en En | MEDLINE | ID: mdl-26037160
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Líquida de Alta Presión / Astemizol / Espectrometría de Masas en Tándem Límite: Animals Idioma: En Revista: J Pharm Biomed Anal Año: 2015 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Líquida de Alta Presión / Astemizol / Espectrometría de Masas en Tándem Límite: Animals Idioma: En Revista: J Pharm Biomed Anal Año: 2015 Tipo del documento: Article