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Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization.
Yan, Wenzhong; Qing, Jie; Mei, Hanbing; Mao, Fei; Huang, Jin; Zhu, Jin; Jiang, Hualiang; Liu, Lei; Zhang, Linqi; Li, Jian.
Afiliación
  • Yan W; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. 15901872753@163.com.
  • Qing J; Tsinghua-Peking Center for Life Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. qing282420@163.com.
  • Mei H; School of Medicine, Tsinghua University, Beijing 100084, China. qing282420@163.com.
  • Mao F; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. xiuzhifumhb@126.com.
  • Huang J; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. maofei@ecust.edu.cn.
  • Zhu J; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. huangjin@ecust.edu.cn.
  • Jiang H; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. jinz@ecust.edu.cn.
  • Liu L; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China. hljiang@ecust.edu.cn.
  • Zhang L; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China. hljiang@ecust.edu.cn.
  • Li J; Tsinghua-Peking Center for Life Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. lliu@mail.tsinghua.edu.cn.
Molecules ; 20(6): 10342-59, 2015 Jun 04.
Article en En | MEDLINE | ID: mdl-26053489
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Hepacivirus / Ciclofilina A Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Hepacivirus / Ciclofilina A Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China