Cooperative folding of a polytopic &#945;-helical membrane protein involves a compact N-terminal nucleus and nonnative loops.

Paslawski, Wojciech; Lillelund, Ove K; Kristensen, Julie Veje; Schafer, Nicholas P; Baker, Rosanna P; Urban, Sinisa; Otzen, Daniel E

Cooperative folding of a polytopic α-helical membrane protein involves a compact N-terminal nucleus and nonnative loops.

Paslawski, Wojciech; Lillelund, Ove K; Kristensen, Julie Veje; Schafer, Nicholas P; Baker, Rosanna P; Urban, Sinisa; Otzen, Daniel E.

Afiliación

Paslawski W; Interdisciplinary Nanoscience Center, Department of Molecular Biology and Genetics, Center for Insoluble Protein Structures, Aarhus University, DK-8000 Aarhus C, Denmark;
Lillelund OK; Interdisciplinary Nanoscience Center, Department of Molecular Biology and Genetics, Center for Insoluble Protein Structures, Aarhus University, DK-8000 Aarhus C, Denmark;
Kristensen JV; Interdisciplinary Nanoscience Center, Department of Molecular Biology and Genetics, Center for Insoluble Protein Structures, Aarhus University, DK-8000 Aarhus C, Denmark;
Schafer NP; Interdisciplinary Nanoscience Center, Department of Molecular Biology and Genetics, Center for Insoluble Protein Structures, Aarhus University, DK-8000 Aarhus C, Denmark;
Baker RP; Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Urban S; Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Otzen DE; Interdisciplinary Nanoscience Center, Department of Molecular Biology and Genetics, Center for Insoluble Protein Structures, Aarhus University, DK-8000 Aarhus C, Denmark; dao@inano.au.dk.

Proc Natl Acad Sci U S A ; 112(26): 7978-83, 2015 Jun 30.

Article en En | MEDLINE | ID: mdl-26056273

Asunto(s)

Proteínas de Unión al ADN/metabolismo; Endopeptidasas/metabolismo; Proteínas de Escherichia coli/metabolismo; Proteínas de la Membrana/metabolismo; Pliegue de Proteína; Proteínas de Unión al ADN/química; Endopeptidasas/química; Proteínas de Escherichia coli/química; Cinética; Proteínas de la Membrana/química; Conformación Proteica

Palabras clave

GlpG; folding; kinetics; membrane protein; rhomboid

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Pliegue de Proteína / Proteínas de Escherichia coli / Proteínas de Unión al ADN / Proteínas de la Membrana Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google