Mediastinal Yolk Sac Tumor Producing Protein Induced by Vitamin K Absence or Antagonist-II.
Intern Med
; 54(12): 1531-6, 2015.
Article
en En
| MEDLINE
| ID: mdl-26073245
ABSTRACT
Extragonadal yolk sac tumors (YSTs) are rare. We herein report the case of a 66-year-old man with mediastinal, lung and liver tumors. The largest mass was located in the liver and contained a high concentration of protein induced by vitamin K absence or antagonist-II (PIVKA-II) and alpha-fetoprotein. Therefore, the lesion was difficult to distinguish from hepatocellular carcinoma. Finally, YST was diagnosed based on the results of a liver biopsy. Although chemotherapy was effective, the patient died of respiratory failure. The autopsy revealed primary mediastinal YST. In the current report, we describe this case of PIVKA-II-producing YST and review previous cases of PIVKA-II-producing tumors other than hepatoma.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Precursores de Proteínas
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Vitamina K
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Protrombina
/
Biomarcadores
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Alfa-Fetoproteínas
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Biomarcadores de Tumor
/
Tumor del Seno Endodérmico
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Neoplasias Hepáticas
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Neoplasias Pulmonares
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Neoplasias del Mediastino
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
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Humans
/
Male
Idioma:
En
Revista:
Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Japón