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Evaluation of intravenous regional perfusion with amphotericin B and dimethylsulfoxide to treat horses for pythiosis of a limb.
Dória, Renata G S; Carvalho, Mariana B; Freitas, Silvio H; Laskoski, Luciane M; Colodel, Edson M; Mendonça, Fábio S; Silva, Marco A G; Grigoletto, Renan; Fantinato Neto, Paulo.
Afiliación
  • Dória RG; Department of Veterinary Medicine, University of São Paulo, Duque de Caxias Norte ave 225, Pirassununga, ZIP 13635-900, SP, Brazil. redoria@usp.br.
  • Carvalho MB; Department of Veterinary Medicine, University of Cuiabá, Cuiabá, MT, Brazil. mama_buenocarvalho@hotmial.com.
  • Freitas SH; Department of Veterinary Medicine, University of São Paulo, Duque de Caxias Norte ave 225, Pirassununga, ZIP 13635-900, SP, Brazil. shfreitas@terra.com.br.
  • Laskoski LM; Department of Veterinary Medicine, Federal University of Paraná, Curitiba, PR, Brazil. luciane-laskoski@hotmail.com.
  • Colodel EM; Department of Veterinary Pathology, Federal University of Mato Grosso, Cuiabá, MT, Brazil. moleta@gmail.com.
  • Mendonça FS; Department of Morphology and Physiology, Federal Rural University of Pernambuco, Recife, PE, Brazil. mendoncafs@yahoo.com.br.
  • Silva MA; Department of Veterinary Medicine, Federal University of Tocantins, Araguaína, TO, Brazil. silva_vet@hotmail.com.
  • Grigoletto R; Department of Veterinary Medicine, University of São Paulo, Duque de Caxias Norte ave 225, Pirassununga, ZIP 13635-900, SP, Brazil. renangrigoletto@gmail.com.
  • Fantinato Neto P; Department of Veterinary Medicine, University of São Paulo, Duque de Caxias Norte ave 225, Pirassununga, ZIP 13635-900, SP, Brazil. fantinatont@gmail.com.
BMC Vet Res ; 11: 152, 2015 Jul 16.
Article en En | MEDLINE | ID: mdl-26174778
ABSTRACT

BACKGROUND:

Treatment for horses with pythiosis of a limb is challenging. This study aims to evaluate the effects of administering amphotericin B in a 10 % solution of dimethylsulfoxide by intravenous regional limb perfusion (IRLP) to treat horses for cutaneous pythiosis of a limb.

RESULTS:

All 15 of the horses treated had complete resolutions of their lesion between 6 to 9 weeks after a single IRLP treatment. No complications were observed at the site of venipuncture for IRLP. Before initiation of treatment, there was anemia and marked leucocytosis which resolved following treatment. Serum biochemistry showed no significant changes.

CONCLUSIONS:

IRLP administration of amphotericin B in a 10 % DMSO solution was easily performed, relatively inexpensive and an effective treatment for treating horses for pythiosis of a limb and resolved the infection with no complications.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pythium / Anfotericina B / Dimetilsulfóxido / Pitiosis / Enfermedades de los Caballos Límite: Animals Idioma: En Revista: BMC Vet Res Asunto de la revista: MEDICINA VETERINARIA Año: 2015 Tipo del documento: Article País de afiliación: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pythium / Anfotericina B / Dimetilsulfóxido / Pitiosis / Enfermedades de los Caballos Límite: Animals Idioma: En Revista: BMC Vet Res Asunto de la revista: MEDICINA VETERINARIA Año: 2015 Tipo del documento: Article País de afiliación: Brasil