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Quantitative bioanalysis of antibody-conjugated payload in monkey plasma using a hybrid immuno-capture LC-MS/MS approach: Assay development, validation, and a case study.
Liu, Ang; Kozhich, Alexander; Passmore, David; Gu, Huidong; Wong, Richard; Zambito, Frank; Rangan, Vangipuram S; Myler, Heather; Aubry, Anne-Françoise; Arnold, Mark E; Wang, Jian.
Afiliación
  • Liu A; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA. Electronic address: ang.liu@bms.com.
  • Kozhich A; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Passmore D; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA 94063, USA.
  • Gu H; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Wong R; Bioanalytical and Discovery Analytical Sciences, Bristol-Myers Squibb, Pennington, NJ 08534, USA.
  • Zambito F; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Rangan VS; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA 94063, USA.
  • Myler H; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Aubry AF; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Arnold ME; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Wang J; Analytical and Bioanalytical Development, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1002: 54-62, 2015 Oct 01.
Article en En | MEDLINE | ID: mdl-26310897
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Liquida / Haplorrinos / Inmunoconjugados / Espectrometría de Masas en Tándem Límite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2015 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Liquida / Haplorrinos / Inmunoconjugados / Espectrometría de Masas en Tándem Límite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2015 Tipo del documento: Article