Citrem modulates internal nanostructure of glyceryl monooleate dispersions and bypasses complement activation: Towards development of safe tunable intravenous lipid nanocarriers.

Wibroe, Peter P; Mat Azmi, Intan D; Nilsson, Christa; Yaghmur, Anan; Moghimi, S Moein

Wibroe, Peter P; Mat Azmi, Intan D; Nilsson, Christa; Yaghmur, Anan; Moghimi, S Moein.

Afiliación

Wibroe PP; Nanomedicine Laboratory, Centre for Pharmaceutical Nanotechnology and Nanotoxicology, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen Ø, Denmark.
Mat Azmi ID; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen Ø, Denmark.
Nilsson C; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen Ø, Denmark.
Yaghmur A; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen Ø, Denmark.
Moghimi SM; Nanomedicine Laboratory, Centre for Pharmaceutical Nanotechnology and Nanotoxicology, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen Ø, Denmark; NanoScience Centre, University of Copenhagen, Copenhagen Ø, Denmark. Electronic address: moein.moghim

Nanomedicine ; 11(8): 1909-14, 2015 Nov.

Article en En | MEDLINE | ID: mdl-26348655

Asunto(s)

Ácido Cítrico/análogos & derivados; Portadores de Fármacos/química; Excipientes/química; Glicéridos/química; Nanoestructuras/química; Triglicéridos/química; Ácido Cítrico/efectos adversos; Activación de Complemento/efectos de los fármacos; Portadores de Fármacos/efectos adversos; Esterificación; Excipientes/efectos adversos; Glicéridos/efectos adversos; Humanos; Cristales Líquidos/efectos adversos; Cristales Líquidos/química; Nanoestructuras/efectos adversos; Dispersión del Ángulo Pequeño; Triglicéridos/efectos adversos; Difracción de Rayos X

Palabras clave

Citrem; Complement system; Hexosomes; Hierarchical materials; Synchrotron small-angle X-ray scattering (SAXS)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triglicéridos / Portadores de Fármacos / Ácido Cítrico / Nanoestructuras / Excipientes / Glicéridos Límite: Humans Idioma: En Revista: Nanomedicine Asunto de la revista: BIOTECNOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Dinamarca

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