[Oral hairy leukoplakia induced by topical steroids]. / Leucoplasie orale chevelue induite par une corticothérapie locale.
Ann Dermatol Venereol
; 142(10): 572-6, 2015 Oct.
Article
en Fr
| MEDLINE
| ID: mdl-26362131
ABSTRACT
BACKGROUND:
Oral hairy leukoplakia (OHL) is an EBV-associated condition of the oral mucosa, which is often painless. It is found predominantly in HIV-positive patients and is considered a clinical indicator of immunosuppression. OHL has rarely been described in HIV-negative patients, being found most often in association with iatrogenic immunosuppression. OHL induced by topical steroids remains extremely rare. PATIENTS ANDMETHODS:
An 81-year-old HIV-negative woman, treated for 3 months with topical steroids for oral lichen planus, developed an asymptomatic white, corrugated, non-removable plaque with vertical folds on the lateral edge of the tongue. Associated oral candidiasis was noted. Based upon histological findings and in situ hybridisation showing numerous EBV-infected epithelial cells, a diagnosis of oral hairy leucoplakia was made. DISCUSSION ANDCONCLUSION:
To our knowledge, we report herein only the second recorded case of OHL induced strictly by topical steroids. Self-medication and poor adherence to dosage recommendations were noted in the patient's medical history. Physicians must be aware of the rare but nevertheless possible adverse events associated with topical steroid use, particularly when such medication is prescribed over a long period for inflammatory diseases of the oral mucosa.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Valerato de Betametasona
/
Clobetasol
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Liquen Plano Oral
/
Leucoplasia Vellosa
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Antiinflamatorios
Tipo de estudio:
Guideline
Límite:
Aged80
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Female
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Humans
Idioma:
Fr
Revista:
Ann Dermatol Venereol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Francia