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Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs.
Osborn, Maire F; Alterman, Julia F; Nikan, Mehran; Cao, Hong; Didiot, Marie C; Hassler, Matthew R; Coles, Andrew H; Khvorova, Anastasia.
Afiliación
  • Osborn MF; RNA Therapeutics Institute, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Alterman JF; RNA Therapeutics Institute, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Nikan M; RNA Therapeutics Institute, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Cao H; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Didiot MC; RNA Therapeutics Institute, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Hassler MR; RNA Therapeutics Institute, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Coles AH; RNA Therapeutics Institute, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Khvorova A; RNA Therapeutics Institute, Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA anastasia.khvorova@umassmed.edu.
Nucleic Acids Res ; 43(18): 8664-72, 2015 Oct 15.
Article en En | MEDLINE | ID: mdl-26400165

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Interferente Pequeño / Interferencia de ARN / Guanabenzo Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Interferente Pequeño / Interferencia de ARN / Guanabenzo Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos