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Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening.
Ruggeri, Chiara; Drinkwater, Nyssa; Sivaraman, Komagal Kannan; Bamert, Rebecca S; McGowan, Sheena; Paiardini, Alessandro.
Afiliación
  • Ruggeri C; Dipartimento di Scienze biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185, Roma, Italy.
  • Drinkwater N; Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia.
  • Sivaraman KK; Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia.
  • Bamert RS; Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia.
  • McGowan S; Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia.
  • Paiardini A; Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185, Roma, Italy.
PLoS One ; 10(9): e0138957, 2015.
Article en En | MEDLINE | ID: mdl-26406322
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Inhibidores de Proteasas / Biología Computacional / Aminopeptidasas / Antimaláricos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Italia
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Inhibidores de Proteasas / Biología Computacional / Aminopeptidasas / Antimaláricos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Italia