Intracellular Zn(2+) detection with quantum dot-based FLIM nanosensors.

Ripoll, Consuelo; Martin, Miguel; Roldan, Mar; Talavera, Eva M; Orte, Angel; Ruedas-Rama, Maria J

Ripoll, Consuelo; Martin, Miguel; Roldan, Mar; Talavera, Eva M; Orte, Angel; Ruedas-Rama, Maria J.

Afiliación

Ripoll C; Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain. angelort@ugr.es mjruedas@ugr.es.
Martin M; GENYO, Pfizer-University of Granada-Junta de Andalucia Centre for Genomics and Oncological Research, Avda Ilustracion 114, PTS, 18016 Granada, Spain.
Roldan M; GENYO, Pfizer-University of Granada-Junta de Andalucia Centre for Genomics and Oncological Research, Avda Ilustracion 114, PTS, 18016 Granada, Spain.
Talavera EM; Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain. angelort@ugr.es mjruedas@ugr.es.
Orte A; Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain. angelort@ugr.es mjruedas@ugr.es.
Ruedas-Rama MJ; Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain. angelort@ugr.es mjruedas@ugr.es.

Chem Commun (Camb) ; 51(95): 16964-7, 2015 Dec 11.

Article en En | MEDLINE | ID: mdl-26443308

ABSTRACT

ABSTRACT

Fluorescence Lifetime Imaging Microscopy (FLIM) has been employed for the detection of intracellular Zn(2+) levels, implicated in various signalling pathways, using a family of quantum dot (QD) nanosensors. The sensing mechanism was based on photoinduced electron transfer (PET) between an azacycle receptor group and the QD nanoparticles.

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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article

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