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A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms.
Derrick, Jeffrey S; Kerr, Richard A; Nam, Younwoo; Oh, Shin Bi; Lee, Hyuck Jin; Earnest, Kaylin G; Suh, Nayoung; Peck, Kristy L; Ozbil, Mehmet; Korshavn, Kyle J; Ramamoorthy, Ayyalusamy; Prabhakar, Rajeev; Merino, Edward J; Shearer, Jason; Lee, Joo-Yong; Ruotolo, Brandon T; Lim, Mi Hee.
Afiliación
  • Derrick JS; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST) , Ulsan 44919, Korea.
  • Kerr RA; Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.
  • Nam Y; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST) , Ulsan 44919, Korea.
  • Oh SB; Asan Institute for Life Sciences, Asan Medical Center , Seoul 05505, Korea.
  • Lee HJ; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST) , Ulsan 44919, Korea.
  • Earnest KG; Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.
  • Suh N; Department of Chemistry, University of Cincinnati , Cincinnati, Ohio 45221, United States.
  • Peck KL; Asan Institute for Life Sciences, Asan Medical Center , Seoul 05505, Korea.
  • Ozbil M; Department of Chemistry, University of Nevada , Reno 89557, United States.
  • Korshavn KJ; Department of Chemistry, University of Miami , Coral Gables, Florida 33146, United States.
  • Ramamoorthy A; Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.
  • Prabhakar R; Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.
  • Merino EJ; Biophysics, University of Michigan , Ann Arbor, Michigan 48109, United States.
  • Shearer J; Department of Chemistry, University of Miami , Coral Gables, Florida 33146, United States.
  • Lee JY; Department of Chemistry, University of Cincinnati , Cincinnati, Ohio 45221, United States.
  • Ruotolo BT; Department of Chemistry, University of Nevada , Reno 89557, United States.
  • Lim MH; Asan Institute for Life Sciences, Asan Medical Center , Seoul 05505, Korea.
J Am Chem Soc ; 137(46): 14785-97, 2015 Nov 25.
Article en En | MEDLINE | ID: mdl-26575890
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos beta-Amiloides / Amiloide Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos beta-Amiloides / Amiloide Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2015 Tipo del documento: Article