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Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Peters, Owen M; Cabrera, Gabriela Toro; Tran, Helene; Gendron, Tania F; McKeon, Jeanne E; Metterville, Jake; Weiss, Alexandra; Wightman, Nicholas; Salameh, Johnny; Kim, Juyhun; Sun, Huaming; Boylan, Kevin B; Dickson, Dennis; Kennedy, Zack; Lin, Ziqiang; Zhang, Yong-Jie; Daughrity, Lillian; Jung, Chris; Gao, Fen-Biao; Sapp, Peter C; Horvitz, H Robert; Bosco, Daryl A; Brown, Solange P; de Jong, Pieter; Petrucelli, Leonard; Mueller, Chris; Brown, Robert H.
Afiliación
  • Peters OM; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Cabrera GT; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Tran H; Department of Pediatrics and Gene Therapy Center University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Gendron TF; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • McKeon JE; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL 32224, USA.
  • Metterville J; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Weiss A; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Wightman N; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Salameh J; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Kim J; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Sun H; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205.
  • Boylan KB; Department of Pediatrics and Gene Therapy Center University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Dickson D; Department of Neurology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, Florida 32224, USA.
  • Kennedy Z; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL 32224, USA.
  • Lin Z; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Zhang YJ; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Daughrity L; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL 32224, USA.
  • Jung C; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL 32224, USA.
  • Gao FB; Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, California 94609.
  • Sapp PC; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Horvitz HR; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Bosco DA; Department of Biology, and McGovern Institute for Brain Research, 77 Massachusetts Avenue, Massachusetts Institute of Technology, Cambridge, MA 02139, H.R.H. is an Investigator of the Howard Hughes Medical Institute.
  • Brown SP; Department of Biology, and McGovern Institute for Brain Research, 77 Massachusetts Avenue, Massachusetts Institute of Technology, Cambridge, MA 02139, H.R.H. is an Investigator of the Howard Hughes Medical Institute.
  • de Jong P; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Petrucelli L; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205.
  • Mueller C; Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, California 94609.
  • Brown RH; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL 32224, USA.
Neuron ; 88(5): 902-909, 2015 Dec 02.
Article en En | MEDLINE | ID: mdl-26637797
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas / Expansión de las Repeticiones de ADN / Dipéptidos / Modelos Animales de Enfermedad / Demencia Frontotemporal / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Neuron Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas / Expansión de las Repeticiones de ADN / Dipéptidos / Modelos Animales de Enfermedad / Demencia Frontotemporal / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Neuron Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos