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Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.
Knight, Elysse M; Ruiz, Henry H; Kim, Soong Ho; Harte, Jessica C; Hsieh, Wilson; Glabe, Charles; Klein, William L; Attie, Alan D; Buettner, Christoph; Ehrlich, Michelle E; Gandy, Sam.
Afiliación
  • Knight EM; Departments of Neurology and Psychiatry, and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, 10029, USA. elysseknight@gmail.com.
  • Ruiz HH; Diabetes, Obesity, and Metabolism Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Kim SH; Departments of Neurology and Psychiatry, and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, 10029, USA.
  • Harte JC; Departments of Neurology and Psychiatry, and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, 10029, USA.
  • Hsieh W; Departments of Neurology and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, 10029, USA.
  • Glabe C; Diabetes, Obesity, and Metabolism Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Klein WL; Universty of California, Irvine, CA, 92697, USA.
  • Attie AD; Biochemistry Department, Faculty of Science and Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Buettner C; Department of Neurobiology, Northwestern University, Evanston, IL, 60208, USA.
  • Ehrlich ME; Department of Biochemistry, University of Wisconsin, Madison, WI, 53706, USA.
  • Gandy S; Diabetes, Obesity, and Metabolism Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Acta Neuropathol Commun ; 4: 16, 2016 Feb 25.
Article en En | MEDLINE | ID: mdl-26916443

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Superficie Celular / Diabetes Mellitus Tipo 2 / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Commun Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Superficie Celular / Diabetes Mellitus Tipo 2 / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Commun Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos