Facile synthesis of substituted 3-aminofurans through a tandem reaction of N-sulfonyl-1,2,3-triazoles with propargyl alcohols.
Org Biomol Chem
; 14(16): 3878-82, 2016 Apr 28.
Article
en En
| MEDLINE
| ID: mdl-26952826
ABSTRACT
A relay catalysis strategy for substituted 3-aminofurans synthesis has been developed. This transformation involves a tandem reaction sequence through aza-vinyl-rhodium(ii) carbene O-H bond insertion, thermal propargyl-Claisen rearrangement and gold(i)-catalyzed intramolecular cyclization. More importantly, the current strategy employs simple feedstocks as starting materials, providing substituted 3-aminofurans in a highly efficient manner.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Triazoles
/
Propanoles
/
Alquinos
/
Furanos
Idioma:
En
Revista:
Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2016
Tipo del documento:
Article