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ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models.
Brooks, Danielle L Peacock; Schwab, Luciana P; Krutilina, Raisa; Parke, Deanna N; Sethuraman, Aarti; Hoogewijs, David; Schörg, Alexandra; Gotwald, Lauren; Fan, Meiyun; Wenger, Roland H; Seagroves, Tiffany N.
Afiliación
  • Brooks DL; Center for Cancer Research and the Department of Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
  • Schwab LP; Present address: National Cancer Institute, Center for Cancer Research, Women's Malignancies Branch, Bethesda, MD, 20892, USA.
  • Krutilina R; Center for Cancer Research and the Department of Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
  • Parke DN; Center for Cancer Research and the Department of Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
  • Sethuraman A; Center for Cancer Research and the Department of Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
  • Hoogewijs D; Center for Cancer Research and the Department of Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
  • Schörg A; Institute of Physiology and Zürich Center for Integrative Human Physiology, University of Zürich, CH-8057, Zürich, Switzerland.
  • Gotwald L; Present address: Institute of Physiology, University of Duisburg-Essen, 45122, Essen, Germany.
  • Fan M; Institute of Physiology and Zürich Center for Integrative Human Physiology, University of Zürich, CH-8057, Zürich, Switzerland.
  • Wenger RH; Center for Cancer Research and the Department of Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
  • Seagroves TN; Center for Cancer Research and the Department of Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Mol Cancer ; 15: 26, 2016 Mar 22.
Article en En | MEDLINE | ID: mdl-27001172

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias de la Mama / Integrina alfa6 / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Subunidad alfa del Factor 1 Inducible por Hipoxia / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Mol Cancer Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias de la Mama / Integrina alfa6 / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Subunidad alfa del Factor 1 Inducible por Hipoxia / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Mol Cancer Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos