Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis.

Qin, Hai-De; Liao, Xiao-Yu; Chen, Yuan-Bin; Huang, Shao-Yi; Xue, Wen-Qiong; Li, Fang-Fang; Ge, Xiao-Song; Liu, De-Qing; Cai, Qiuyin; Long, Jirong; Li, Xi-Zhao; Hu, Ye-Zhu; Zhang, Shao-Dan; Zhang, Lan-Jun; Lehrman, Benjamin; Scott, Alan F; Lin, Dongxin; Zeng, Yi-Xin; Shugart, Yin Yao; Jia, Wei-Hua

Qin, Hai-De; Liao, Xiao-Yu; Chen, Yuan-Bin; Huang, Shao-Yi; Xue, Wen-Qiong; Li, Fang-Fang; Ge, Xiao-Song; Liu, De-Qing; Cai, Qiuyin; Long, Jirong; Li, Xi-Zhao; Hu, Ye-Zhu; Zhang, Shao-Dan; Zhang, Lan-Jun; Lehrman, Benjamin; Scott, Alan F; Lin, Dongxin; Zeng, Yi-Xin; Shugart, Yin Yao; Jia, Wei-Hua.

Afiliación

Qin HD; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China; Unit on Statistical Genomics, Division of Intramural Research Programs, National Institute of Mental Health, NIH, Bethesda, MD 20892, U
Liao XY; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Chen YB; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Huang SY; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Xue WQ; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Li FF; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Ge XS; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China; The Affiliated Hospital of Jiangnan University, Wuxi 214062, China.
Liu DQ; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center and Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37240, USA.
Long J; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center and Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37240, USA.
Li XZ; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Hu YZ; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Zhang SD; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Zhang LJ; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Lehrman B; Unit on Statistical Genomics, Division of Intramural Research Programs, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Scott AF; McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Lin D; State Key Laboratory of Molecular Oncology, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100021, China.
Zeng YX; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Shugart YY; Unit on Statistical Genomics, Division of Intramural Research Programs, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA. Electronic address: kay1yao@mail.nih.gov.
Jia WH; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China. Electronic address: jiawh@sysucc.org.cn.

Am J Hum Genet ; 98(4): 709-27, 2016 Apr 07.

Article en En | MEDLINE | ID: mdl-27058444

Asunto(s)

Carcinogénesis/genética; Carcinoma de Células Escamosas/diagnóstico; Carcinoma de Células Escamosas/genética; Neoplasias Esofágicas/diagnóstico; Neoplasias Esofágicas/genética; Regulación Neoplásica de la Expresión Génica; Adulto; Anciano; Anciano de 80 o más Años; Animales; Proteínas Portadoras/genética; Proteínas de Ciclo Celular/genética; Línea Celular Tumoral; Proliferación Celular/genética; Variaciones en el Número de Copia de ADN; Carcinoma de Células Escamosas de Esófago; Exoma; Proteína de Dominio de Muerte Asociada a Fas/genética; Femenino; Perfilación de la Expresión Génica; Estudios de Asociación Genética; Humanos; Masculino; Proteínas de la Membrana/genética; Ratones; Ratones Endogámicos BALB C; MicroARNs/genética; Persona de Mediana Edad; Mutación; Proteínas del Tejido Nervioso/genética; Pronóstico; Selección Genética; Transactivadores/genética; Ensayos Antitumor por Modelo de Xenoinjerto

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Regulación Neoplásica de la Expresión Génica / Carcinogénesis Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Hum Genet Año: 2016 Tipo del documento: Article

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